If you’ve ever looked in the mirror and wished your skin looked a little firmer, smoother, or just younger, you’re not alone. I’ve been there too. After hearing so many good things about Neocutis Bio Serum (Provider) and SkinMedica TNS, I decided to test them both myself. I wanted to find out which one actually works and is worth the money.
Here’s a quick heads-up: both are great, but one became my favourite.
Why I Tried These Two Serums
Like many women in their 30s, I began to notice fine lines around my eyes and mouth. My skin wasn’t as bright or bouncy as it had been before. I didn’t want to jump into anything too harsh, so I went for anti-ageing serums that are known for real results.
I kept seeing Neocutis Bio Serum and SkinMedica TNS Advanced+ Serum mentioned in dermatologists’ offices, online reviews, and beauty forums. Both are popular high-end options that promise smoother, younger-looking skin. But are they really that different?
First Impressions
Neocutis Bio Serum
When I first applied Neocutis Bio Serum, I noticed how lightweight it felt. It absorbed quickly and left no sticky residue. The texture is silky and smooth, almost like a soft primer.
The scent is very mild, which I appreciate because I have sensitive skin. Within the first week, my skin already felt softer and more hydrated.
Highlighted Benefit: It made my skin feel instantly smoother and plumper, almost as if it had undergone a little ‘glow-up’ moment.
SkinMedica TNS Advanced+ Serum
SkinMedica TNS Serum has a strong reputation. It comes in a dual-chamber bottle, with one side holding growth factors and the other containing peptides. When you use it, both sides mix to help your skin repair and renew.
At first, I wasn’t a fan of the smell (it was a bit clinical), but I eventually grew accustomed to it. After about 2 weeks, I started to notice real results: my skin looked tighter, especially around the cheeks and jawline.
Highlighted Benefit: It gave my skin a firmer, lifted look, which I hadn’t experienced with other serums.
Ingredients Breakdown: What’s Inside These Serums?
Neocutis Bio Serum
- Growth factors (for cell renewal)
- Hyaluronic acid (for deep hydration)
- Peptides (for firmness and elasticity)
- Vitamin C (for brightness)
This combo works beautifully if you’re aiming for smoother, glowing skin that feels nourished and healthy.
SkinMedica TNS Serum
- Growth factors (TNS blend with 450+ proteins!)
- Peptides (for tightening)
- Antioxidants (to fight ageing)
- Marine extracts (for this one feels like a ‘spa in a bottle’) are made for real anti-ageing results and visible tightening.
Results After 4 Weeks
After one month, I could really tell the difference between the two.
✅ Neocutis Bio Serum: My skin felt softer, looked brighter, and makeup applied beautifully. It’s perfect for daily use if you want hydration and glow.
✅ SkinMedica TNS Serum: I noticed a visible lift and fewer fine lines. It made my skin look younger and more even.
If I had to describe it in one word, it would be transformative.
Price & Value
Let’s be real — both are pricey.
💰 Neocutis Bio Serum: Around $290
💰 SkinMedica TNS Serum: Around $295
But here’s the thing: a little goes a long way with both. If you use them regularly, one bottle can last about two to three months.
For me, SkinMedica felt more like an investment, while Neocutis was more of a luxury comfort.
Which One Is Right for You?
| Texture | Silky, lightweight | Richer, dual-chamber |
| Main Focus | Hydration + glow | Firmness + anti-aging |
| Skin Type | Normal, dry, sensitive | Mature, dull, or sagging |
| Scent | Mild | Slightly medicinal |
| Visible Results | Softer, radiant skin | Lifted, tighter skin |
👉 If you want glowing, hydrated skin, go with Neocutis Bio Serum.
👉 If you want firmer, tighter skin and fewer lines, SkinMedica TNS Serum is your winner.
My Personal Verdict
As much as I love both, SkinMedica TNS Advanced+ Serum gave me the most noticeable results. My skin looked firmer and smoother after just a few weeks.
Still, I reach for Neocutis Bio Serum when my skin feels dry or sensitive. It’s like comfort food for my face.
So, if you can afford it, try both and see how your skin responds. However, if you want faster and more visible tightening, opt for SkinMedica.
Final Thoughts
Both Neocutis Bio Serum and SkinMedica TNS Advanced+ Serum are great skincare investments. Your choice depends on what your skin needs most: hydration and glow, or tightening and firmness.
If I had to pick one?
SkinMedica TNS, since the lift and smoothness were hard to ignore.
FAQs
Yes, but not at the same time. Use one in the morning and the other at night for best results.
Yes, although SkinMedica may cause slight tingling at first, this is a normal side effect. Always patch-test first.
For most people, consistent use for around 2 to 4 weeks is recommended.
